CRFB5a, a Subtype of Japanese Eel (<i>Anguilla japonica</i>) Type I IFN Receptor, Regulates Host Antiviral and Antimicrobial Functions through Activation of IRF3/IRF7 and LEAP2

IFNAR1, one of the type I IFN receptors, is crucial to mammalian host defense against viral invasion. However, largely unknown is the immunological role of the fish teleost protein IFNAR1, also known as CRFB5. We have successfully cloned the whole cDNA of the Japanese eel’s (<i>Anguilla japoni...

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Bibliographic Details
Main Authors: Tianyu Wang, Peng Lin, Yilei Wang, Xiaojian Lai, Pengyun Chen, Fuyan Li, Jianjun Feng
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Animals
Subjects:
Online Access:https://www.mdpi.com/2076-2615/13/19/3157