ATF3-Induced Mammary Tumors Exhibit Molecular Features of Human Basal-Like Breast Cancer

ATF3-Induced Mammary Tumors Exhibit Molecular Features of Human Basal-Like Breast Cancer

Basal-like breast cancer (BLBC) is an aggressive and deadly subtype of human breast cancer that is highly metastatic, displays stem-cell like features, and has limited treatment options. Therefore, developing and characterizing preclinical mouse models with tumors that resemble BLBC is important for...

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Bibliographic Details
Main Authors: Leqin Yan, Sally Gaddis, Luis Della Coletta, John Repass, Katherine Leslie Powell, Melissa S. Simper, Yueping Chen, Michelle Byrom, Yi Zhong, Kevin Lin, Bin Liu, Yue Lu, Jianjun Shen, Michael C. MacLeod
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:International Journal of Molecular Sciences
Subjects:
ATF3
mouse model
breast cancer
basal-like
RNA-Seq
miRNA
Online Access:https://www.mdpi.com/1422-0067/22/5/2353

Internet

https://www.mdpi.com/1422-0067/22/5/2353

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