Gain of UBE2D1 facilitates hepatocellular carcinoma progression and is associated with DNA damage caused by continuous IL-6

Gain of UBE2D1 facilitates hepatocellular carcinoma progression and is associated with DNA damage caused by continuous IL-6

Abstract Background Hepatocellular carcinoma (HCC) is the most common type of liver cancer with increasing incidence and poor prognosis. Ubiquitination regulators are reported to play crucial roles in HCC carcinogenesis. UBE2D1, one of family member of E2 ubiquitin conjugating enzyme, mediates the u...

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Bibliographic Details
Main Authors: Chuanchuan Zhou, Fengrui Bi, Jihang Yuan, Fu Yang, Shuhan Sun
Format: Article
Language:English
Published: BMC 2018-11-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
UBE2D1
Hepatocellular carcinoma
Copy number variations
Continuous IL-6
RAD51B
Online Access:http://link.springer.com/article/10.1186/s13046-018-0951-8

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http://link.springer.com/article/10.1186/s13046-018-0951-8

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