Negative Binomial Mixed Models for Analyzing Longitudinal Microbiome Data

The metagenomics sequencing data provide valuable resources for investigating the associations between the microbiome and host environmental/clinical factors and the dynamic changes of microbial abundance over time. The distinct properties of microbiome measurements include varied total sequence rea...

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Bibliographic Details
Main Authors: Xinyan Zhang, Yu-Fang Pei, Lei Zhang, Boyi Guo, Amanda H. Pendegraft, Wenzhuo Zhuang, Nengjun Yi
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Microbiology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2018.01683/full