Suppressing dengue-2 infection by chemical inhibition of Aedes aegypti host factors.

Dengue virus host factors (DENV HFs) that are essential for the completion of the infection cycle in the mosquito vector and vertebrate host represent potent targets for transmission blocking. Here we investigated whether known mammalian DENV HF inhibitors could influence virus infection in the arth...

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Bibliographic Details
Main Authors: Seokyoung Kang, Alicia R Shields, Natapong Jupatanakul, George Dimopoulos
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-08-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC4125141?pdf=render