Detection of Androgen Receptor Variant 7 (<i>ARV7)</i> mRNA Levels in EpCAM-Enriched CTC Fractions for Monitoring Response to Androgen Targeting Therapies in Prostate Cancer

Detection of Androgen Receptor Variant 7 (<i>ARV7)</i> mRNA Levels in EpCAM-Enriched CTC Fractions for Monitoring Response to Androgen Targeting Therapies in Prostate Cancer

Expression of the androgen receptor splice variant 7 (<i>ARV7)</i> in circulating tumor cells (CTCs) has been associated with resistance towards novel androgen receptor (AR)-targeting therapies. While a multitude of ARV7 detection approaches have been developed, the simultaneous enumerat...

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Bibliographic Details
Main Authors: Claudia Hille, Tobias M. Gorges, Sabine Riethdorf, Martine Mazel, Thomas Steuber, Gunhild Von Amsberg, Frank König, Sven Peine, Catherine Alix-Panabières, Klaus Pantel
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Cells
Subjects:
prostate cancer
biomarkers
circulating tumor cells
androgen receptor
ARV7
abiraterone
enzalutamide
Online Access:https://www.mdpi.com/2073-4409/8/9/1067

Internet

https://www.mdpi.com/2073-4409/8/9/1067

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