Human NCF1<sup>90H</sup> Variant Promotes IL-23/IL-17—Dependent Mannan-Induced Psoriasis and Psoriatic Arthritis

Recently, a major single nucleotide variant on the NCF1 gene, leading to an amino acid replacement from arginine to histidine at position 90 (NCF1<sup>R90H</sup>), associated with low production of reactive oxygen species (ROS), was found to be causative for several autoimmune diseases....

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Bibliographic Details
Main Authors: Yanpeng Li, Zhilei Li, Kutty Selva Nandakumar, Rikard Holmdahl
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Antioxidants
Subjects:
Online Access:https://www.mdpi.com/2076-3921/12/7/1348