The Increased Expression of Regulator of G-Protein Signaling 2 (RGS2) Inhibits Insulin-Induced Akt Phosphorylation and Is Associated with Uncontrolled Glycemia in Patients with Type 2 Diabetes

The Increased Expression of Regulator of G-Protein Signaling 2 (RGS2) Inhibits Insulin-Induced Akt Phosphorylation and Is Associated with Uncontrolled Glycemia in Patients with Type 2 Diabetes

Experimental evidence in mice models has demonstrated that a high regulator of G-protein signaling 2 (RSG2) protein levels precede an insulin resistance state. In the same context, a diet rich in saturated fatty acids induces an increase in RGS2 protein expression, which has been associated with dec...

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Bibliographic Details
Main Authors: J. Gustavo Vazquez-Jimenez, M. Stephanie Corpus-Navarro, J. Miguel Rodriguez-Chavez, Hiram J. Jaramillo-Ramirez, Judith Hernandez-Aranda, Octavio Galindo-Hernandez, J. Rene Machado-Contreras, Marina Trejo-Trejo, Agustin Guerrero-Hernandez, J. Alberto Olivares-Reyes
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Metabolites
Subjects:
Akt protein
HbA1c
human endothelial cells
insulin resistance
palmitic acid
regulator of G-protein signaling 2
Online Access:https://www.mdpi.com/2218-1989/11/2/91

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https://www.mdpi.com/2218-1989/11/2/91

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