The contribution of the acute phase response to the pathogenesis of relapse in chronic-relapsing experimental autoimmune encephalitis models of multiple sclerosis

The contribution of the acute phase response to the pathogenesis of relapse in chronic-relapsing experimental autoimmune encephalitis models of multiple sclerosis

Abstract Background Increased relapse rates in multiple sclerosis (MS) as a consequence of peripheral immune system activation, owing to infection for example, have been widely reported, but the mechanism remains unclear. Acute brain injury models can be exacerbated by augmenting the hepatic acute p...

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Bibliographic Details
Main Authors: Silvy Mardiguian, Emma Ladds, Roberta Turner, Hazel Shepherd, Sandra J. Campbell, Daniel C. Anthony
Format: Article
Language:English
Published: BMC 2017-09-01
Series:Journal of Neuroinflammation
Subjects:
Multiple sclerosis
Lipopolysaccharide
Acute phase response
VCAM-MPIO
Online Access:http://link.springer.com/article/10.1186/s12974-017-0969-4

Internet

http://link.springer.com/article/10.1186/s12974-017-0969-4

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