Non-classical HLA-E restricted CMV 15-mer peptides are recognized by adaptive NK cells and induce memory responses

IntroductionHuman cytomegalovirus (HCMV) reactivation causes complications in immunocompromised patients after hematopoietic stem cell transplantation (HSCT), significantly increasing morbidity and mortality. Adaptive Natural Killer (aNK) cells undergo a persistent reconfiguration in response to HCM...

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Main Authors: Nerea Martín Almazán, Benedetta Maria Sala, Tatyana Sandalova, Yizhe Sun, Tom Resink, Frank Cichocki, Cecilia Söderberg-Nauclér, Jeffrey S. Miller, Adnane Achour, Dhifaf Sarhan
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Immunology
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Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1230718/full