Ectoine Globally Hypomethylates DNA in Skin Cells and Suppresses Cancer Proliferation

Ectoine Globally Hypomethylates DNA in Skin Cells and Suppresses Cancer Proliferation

Epigenetic modifications, mainly aberrant DNA methylation, have been shown to silence the expression of genes involved in epigenetic diseases, including cancer suppression genes. Almost all conventional cancer therapeutic agents, such as the DNA hypomethylation drug 5-aza-2-deoxycytidine, have insur...

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Bibliographic Details
Main Authors: Majjid A. Qaria, Chunyan Xu, Ran Hu, Roua A. Alsubki, Mohamed Yassin Ali, Sethupathy Sivasamy, Kotb A. Attia, Daochen Zhu
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Marine Drugs
Subjects:
ectoine
epigenetic modifications
DNA hypomethylation
skin cells
tumorigenicity
cell proliferation
Online Access:https://www.mdpi.com/1660-3397/21/12/621

Internet

https://www.mdpi.com/1660-3397/21/12/621

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