Differential Expression Analysis of Single-Cell RNA-Seq Data: Current Statistical Approaches and Outstanding Challenges

Differential Expression Analysis of Single-Cell RNA-Seq Data: Current Statistical Approaches and Outstanding Challenges

With the advent of single-cell RNA-sequencing (scRNA-seq), it is possible to measure the expression dynamics of genes at the single-cell level. Through scRNA-seq, a huge amount of expression data for several thousand(s) of genes over million(s) of cells are generated in a single experiment. Differen...

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Bibliographic Details
Main Authors: Samarendra Das, Anil Rai, Shesh N. Rai
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Entropy
Subjects:
scRNA-seq
differential expression analysis
classification
statistical approaches
challenges
Online Access:https://www.mdpi.com/1099-4300/24/7/995

Internet

https://www.mdpi.com/1099-4300/24/7/995

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