The novel visual cycle inhibitor (±)-RPE65-61 protects retinal photoreceptors from light-induced degeneration

The novel visual cycle inhibitor (±)-RPE65-61 protects retinal photoreceptors from light-induced degeneration

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The visual cycle refers to a series of biochemical reactions of retinoids in ocular tissues and supports the vision in vertebrates. The visual cycle regenerates visual pigments chromophore, 11-cis-retinal, and eliminates its toxic byproducts from the retina, supporting visual function and retinal ne...

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Bibliographic Details
Main Authors: Yuhong Wang, Xiang Ma, Parthasarathy Muthuraman, Arun Raja, Aravindan Jayaraman, Konstantin Petrukhin, Christopher L. Cioffi, Jian-Xing Ma, Gennadiy Moiseyev
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9560169/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9560169/?tool=EBI

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