The novel visual cycle inhibitor (±)-RPE65-61 protects retinal photoreceptors from light-induced degeneration
The visual cycle refers to a series of biochemical reactions of retinoids in ocular tissues and supports the vision in vertebrates. The visual cycle regenerates visual pigments chromophore, 11-cis-retinal, and eliminates its toxic byproducts from the retina, supporting visual function and retinal ne...
Main Authors: | Yuhong Wang, Xiang Ma, Parthasarathy Muthuraman, Arun Raja, Aravindan Jayaraman, Konstantin Petrukhin, Christopher L. Cioffi, Jian-Xing Ma, Gennadiy Moiseyev |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2022-01-01
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Series: | PLoS ONE |
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9560169/?tool=EBI |
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