Localization and local translation of Arc/Arg3.1 mRNA at synapses: some observations and paradoxes

Localization and local translation of Arc/Arg3.1 mRNA at synapses: some observations and paradoxes

Arc is a unique immediate early gene whose expression is induced as synapses are being modified during learning. The uniqueness comes from the fact that newly-synthesized Arc mRNA is rapidly transported throughout dendrites where it localizes near synapses that were recently activated. Here we sum...

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Bibliographic Details
Main Authors: Oswald eSteward, Shannon eFarris, Jennifer eDarnell, Sarah J Van Driesche, Patricia Salgado Pirbhoy
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-01-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Transcription, Genetic
imaging
LTP
synaptic plasticity
Dendrite
dendritic spine
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnmol.2014.00101/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnmol.2014.00101/full

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