Triamcinolone acetonide-loaded nanoparticles encapsulated by CD90+ MCSs-derived microvesicles drive anti-inflammatory properties and promote cartilage regeneration after osteoarthritis

Triamcinolone acetonide-loaded nanoparticles encapsulated by CD90+ MCSs-derived microvesicles drive anti-inflammatory properties and promote cartilage regeneration after osteoarthritis

Highlights Long-term injection of glucocorticoids in the knee joint cavity promotes loss of cartilage content. CD90-positive stem cell vesicles encapsulated with Triamcinolone acetonide-loaded nanoparticles have good materials. T-CD90@NPs drive anti-inflammatory properties and promote cartilage rege...

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Bibliographic Details
Main Authors: Yuanlong Li, Qingqiang Tu, Dongmei Xie, Shurui Chen, Kai Gao, Xiaochun Xu, Ziji Zhang, Xifan Mei
Format: Article
Language:English
Published: BMC 2022-03-01
Series:Journal of Nanobiotechnology
Subjects:
Osteoarthritis
Biomimetic nanoparticles
CD90+ MCSs-derived micro-vesicle
Cartilage regeneration
Anti-inflammatory
Online Access:https://doi.org/10.1186/s12951-022-01367-z

Internet

https://doi.org/10.1186/s12951-022-01367-z

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