Novel CCL21-vault nanocapsule intratumoral delivery inhibits lung cancer growth.

Novel CCL21-vault nanocapsule intratumoral delivery inhibits lung cancer growth.

Based on our preclinical findings, we are assessing the efficacy of intratumoral injection of dendritic cells (DC) transduced with an adenoviral vector expressing the secondary lymphoid chemokine (CCL21) gene (Ad-CCL21-DC) in a phase I trial in advanced non-small cell lung cancer (NSCLC). While this...

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Bibliographic Details
Main Authors: Upendra K Kar, Minu K Srivastava, Asa Andersson, Felicita Baratelli, Min Huang, Valerie A Kickhoefer, Steven M Dubinett, Leonard H Rome, Sherven Sharma
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-05-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3086906?pdf=render

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http://europepmc.org/articles/PMC3086906?pdf=render

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