Regional neuroinflammation induced by peripheral infection contributes to fatigue-like symptoms: a [18F]DPA-714 positron emission tomography study in rats

IntroductionA series of symptoms, including fever, widespread pain, fatigue, and even ageusia, have frequently been reported in the context of various infections, such as COVID-19. Although the pathogenic mechanisms underlying an infection causing fever and pain have been well established, the mecha...

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Bibliographic Details
Main Authors: Danxi Li, Di Hu, Yuta Ochi, Wakiko Arakaki, Aya Mawatari, Mika Shigeta, Yuping Wu, Emi Hayashinaka, Hiroyuki Neyama, Tsuyoshi Tahara, Yasuhiro Wada, Feng Li, Hisashi Doi, Yasuyoshi Watanabe, Yilong Cui
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1261256/full