Aflibercept Nanoformulation Inhibits VEGF Expression in Ocular In Vitro Model: A Preliminary Report

Age-related macular degeneration (AMD) is one of the leading causes of blindness in the United States, affecting approximately 11 million patients. AMD is caused primarily by an upregulation of vascular endothelial growth factor (VEGF). In recent years, aflibercept injections have been used to comba...

Full description

Bibliographic Details
Main Authors: Shannon J. Kelly, Anjali Hirani, Vishal Shahidadpury, Aum Solanki, Kathleen Halasz, Sheeba Varghese Gupta, Brian Madow, Vijaykumar Sutariya
Format: Article
Language:English
Published: MDPI AG 2018-09-01
Series:Biomedicines
Subjects:
Online Access:http://www.mdpi.com/2227-9059/6/3/92