Synergistic effects of resveratrol with gemcitabine in pancreatic cancer chemotherapy by inhibiting the c-Met/PARP1 axis

Synergistic effects of resveratrol with gemcitabine in pancreatic cancer chemotherapy by inhibiting the c-Met/PARP1 axis

Objective:. Pancreatic cancer is a highly malignant tumor of the digestive tract with a dismal prognosis. A key challenge of pancreatic cancer is its resistance to chemotherapy. The C-mesenchymal-epithelial transition factor (c-Met)/poly (ADP-ribose) polymerase 1 (PARP1) axis plays an important role...

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Bibliographic Details
Main Authors: Shuai Wu, Jiaqiang Ren, Weikun Qian, Mengyuan Gong, Jie Li, Tao Qin, Simei Zhang, Wunai Zhang, Hao Sun, Zheng Wu, Zheng Wang, Qingyong Ma, Wanxing Duan
Format: Article
Language:English
Published: Wolters Kluwer Health/LWW 2024-12-01
Series:Journal of Pancreatology
Online Access:http://journals.lww.com/10.1097/JP9.0000000000000160

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http://journals.lww.com/10.1097/JP9.0000000000000160

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