Bacterial Genome-Wide Association Identifies Novel Factors That Contribute to Ethionamide and Prothionamide Susceptibility in <named-content content-type="genus-species">Mycobacterium tuberculosis</named-content>

ABSTRACT In Mycobacterium tuberculosis, recent genome-wide association studies have identified a novel constellation of mutations that are correlated with high-level drug resistances. Interpreting the functional importance of the new resistance-associated mutations has been complicated, however, by...

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Bibliographic Details
Main Authors: Nathan D. Hicks, Allison F. Carey, Jian Yang, Yanlin Zhao, Sarah M. Fortune
Format: Article
Language:English
Published: American Society for Microbiology 2019-04-01
Series:mBio
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/mBio.00616-19