Effect of Simvastatin on Lipid Accumulation and the Expression of CXCL16 and Nephrin in Podocyte Induced by Oxidized LDL

Objective: To investigate the effect of simvastatin on lipid accumulation and the expression of CXCL16 and Nephrin in murine podocytes induced by oxidized LDL (OxLDL) in order to explore the mechanism of protection. Methods: Murine podocytes (MPC5) were incubated with OxLDL (80 μg/ml) at different c...

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Bibliographic Details
Main Authors: Li Wang, Xiujun Yao, Qian Li, Shuzhen Sun
Format: Article
Language:English
Published: Taylor & Francis Group 2018-03-01
Series:Journal of Investigative Surgery
Subjects:
Online Access:http://dx.doi.org/10.1080/08941939.2016.1278057