Estrogen receptors α, β and GPER in the CNS and trigeminal system - molecular and functional aspects
Abstract Background Migraine occurs 2–3 times more often in females than in males and is in many females associated with the onset of menstruation. The steroid hormone, 17β-estradiol (estrogen, E2), exerts its effects by binding and activating several estrogen receptors (ERs). Calcitonin gene-relate...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-11-01
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Series: | The Journal of Headache and Pain |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s10194-020-01197-0 |