Identifying new therapeutic targets via modulation of protein corona formation by engineered nanoparticles.

Identifying new therapeutic targets via modulation of protein corona formation by engineered nanoparticles.

We introduce a promising methodology to identify new therapeutic targets in cancer. Proteins bind to nanoparticles to form a protein corona. We modulate this corona by using surface-engineered nanoparticles, and identify protein composition to provide insight into disease development.Using a family...

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Bibliographic Details
Main Authors: Rochelle R Arvizo, Karuna Giri, Daniel Moyano, Oscar R Miranda, Benjamin Madden, Daniel J McCormick, Resham Bhattacharya, Vincent M Rotello, Jean-Pierre Kocher, Priyabrata Mukherjee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3307759?pdf=render

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http://europepmc.org/articles/PMC3307759?pdf=render

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