Synthesis, Characterization, Theoretical and Experimental Anticancer Evaluation of Novel Cocrystals of 5-Fluorouracil and Schiff Bases against SW480 Colorectal Carcinoma

Synthesis, Characterization, Theoretical and Experimental Anticancer Evaluation of Novel Cocrystals of 5-Fluorouracil and Schiff Bases against SW480 Colorectal Carcinoma

The chemotherapeutic agent known as 5-fluorouracil (5-FU) is an artificial fluoropyrimidine antimetabolite that has been widely used for its antineoplastic properties. Cocrystals of 5-fluorouracil (5-FU) with five different Schiff bases (benzylidene-urea (<b>BU</b>), benzylidene-aniline...

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Bibliographic Details
Main Authors: Farhat Jubeen, Ishrat Jabeen, Usman Aftab, Sadia Noor, Mah e Hareem, Misbah Sultan, Mohsin Kazi
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Pharmaceutics
Subjects:
Schiff bases
MTT assay
computational study
5-FU
cocrystallization
Online Access:https://www.mdpi.com/1999-4923/15/7/1929

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https://www.mdpi.com/1999-4923/15/7/1929

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