Diminished Neutralization Capacity of SARS-CoV-2 Omicron BA.1 in Donor Plasma Collected from January to March 2021

Diminished Neutralization Capacity of SARS-CoV-2 Omicron BA.1 in Donor Plasma Collected from January to March 2021

ABSTRACT The 50% plaque reduction neutralization assay (PRNT50) has been previously used to assess the neutralization capacity of donor plasma against wild-type and variant of concern (VOC) severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Emerging data suggest that plasma with an anti-S...

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Bibliographic Details
Main Authors: Yi-Chan J. Lin, David H. Evans, Ninette F. Robbins, Guillermo Orjuela, Kento T. Abe, Bhavisha Rathod, Karen Colwill, Anne-Claude Gingras, Ashleigh Tuite, Qi-Long Yi, Sheila F. O’Brien, Steven J. Drews
Format: Article
Language:English
Published: American Society for Microbiology 2023-08-01
Series:Microbiology Spectrum
Subjects:
COVID-19 convalescent plasma
SARS-CoV-2 antibody
Omicron
neutralizing antibody
plaque reduction neutralization
method comparisons
Online Access:https://journals.asm.org/doi/10.1128/spectrum.05256-22

Internet

https://journals.asm.org/doi/10.1128/spectrum.05256-22

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