Molecular dynamics simulations of a multicellular model with cell-cell interactions and Hippo signaling pathway.

Molecular dynamics simulations of a multicellular model with cell-cell interactions and Hippo signaling pathway.

Show other versions (1)

The transcriptional coactivator Yes-associated protein (YAP)/transcriptional co-activator with PDZ binding motif (TAZ) induces cell proliferation through nuclear localization at low cell density. Conversely, at extremely high cell density, the Hippo pathway, which regulates YAP/TAZ, is activated. Th...

Full description

Bibliographic Details
Main Authors: Toshihito Umegaki, Hisashi Moriizumi, Fumiko Ogushi, Mutsuhiro Takekawa, Takashi Suzuki
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-11-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1012536

Internet

https://doi.org/10.1371/journal.pcbi.1012536

Similar Items