Myeloma plasma cells alter the bone marrow microenvironment by stimulating the proliferation of mesenchymal stromal cells

Multiple myeloma is an incurable hematologic cancer characterized by the clonal proliferation of malignant plasma cells within the bone marrow. Numerous studies suggest that the myeloma plasma cells occupy and alter the stromal tissue of the bone marrow as a means of enhancing their survival and gro...

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Bibliographic Details
Main Authors: Jacqueline E. Noll, Sharon A. Williams, Christine M. Tong, Hongsheng Wang, Julie M. Quach, Louise E. Purton, Katherine Pilkington, Luen B. To, Andreas Evdokiou, Stan Gronthos, Andrew C.W. Zannettino
Format: Article
Language:English
Published: Ferrata Storti Foundation 2014-01-01
Series:Haematologica
Online Access:https://haematologica.org/article/view/6893