A quality-by-design eco-friendly UV-HPLC method for the determination of four drugs used to treat symptoms of common cold and COVID-19

Abstract An optimization approach based on full factorial design was employed for developing an HPLC–UV method for simultaneous determination of a quaternary mixture used for the treatment of symptoms related to common cold and COVID-19. The quaternary mixture is composed of paracetamol, levocetiriz...

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Bibliographic Details
Main Authors: Nora A. Abdallah, Mona E. Fathy, Manar M. Tolba, Amina M. El-Brashy, Fawzia A. Ibrahim
Format: Article
Language:English
Published: Nature Portfolio 2023-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-28737-3