Coordinated linear and rotational movements of endothelial cells compartmentalized by VE-cadherin drive angiogenic sprouting

Summary: Angiogenesis is a sequential process to extend new blood vessels from preexisting ones by sprouting and branching. During angiogenesis, endothelial cells (ECs) exhibit inhomogeneous multicellular behaviors referred to as “cell mixing,” in which ECs repetitively exchange their relative posit...

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Bibliographic Details
Main Authors: Kazuo Tonami, Tatsuya Hayashi, Yasunobu Uchijima, Masahiro Kanai, Fumitaka Yura, Jun Mada, Kei Sugahara, Yukiko Kurihara, Yuri Kominami, Toshiyuki Ushijima, Naoko Takubo, Xiaoxiao Liu, Hideto Tozawa, Yoshimitsu Kanai, Tetsuji Tokihiro, Hiroki Kurihara
Format: Article
Language:English
Published: Elsevier 2023-07-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223011288