Automated three-dimensional detection and shape classification of dendritic spines from fluorescence microscopy images.

Automated three-dimensional detection and shape classification of dendritic spines from fluorescence microscopy images.

A fundamental challenge in understanding how dendritic spine morphology controls learning and memory has been quantifying three-dimensional (3D) spine shapes with sufficient precision to distinguish morphologic types, and sufficient throughput for robust statistical analysis. The necessity to analyz...

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Bibliographic Details
Main Authors: Alfredo Rodriguez, Douglas B Ehlenberger, Dara L Dickstein, Patrick R Hof, Susan L Wearne
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-04-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2292261?pdf=render

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http://europepmc.org/articles/PMC2292261?pdf=render

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