The Anti-Melanogenesis Effect of 3,4-Dihydroxybenzalacetone through Downregulation of Melanosome Maturation and Transportation in B16F10 and Human Epidermal Melanocytes

The Anti-Melanogenesis Effect of 3,4-Dihydroxybenzalacetone through Downregulation of Melanosome Maturation and Transportation in B16F10 and Human Epidermal Melanocytes

The biosynthesis pathway of melanin is a series of oxidative reactions that are catalyzed by melanin-related proteins, including tyrosinase (TYR), tyrosinase-related protein-1 (TRP-1), and tyrosinase-related protein-2 (TRP-2). Reagents or materials with antioxidative or free radical-scavenging activ...

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Bibliographic Details
Main Authors: Yi-Jung Liu, Jia-Ling Lyu, Yueh-Hsiung Kuo, Chen-Yuan Chiu, Kuo-Chiang Wen, Hsiu-Mei Chiang
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:International Journal of Molecular Sciences
Subjects:
3,4-dihydroxybenzalacetone
natural antioxidants
melanogenesis
melanosome maturation
melanosome transport
microphthalmia-associated transcription factor
Online Access:https://www.mdpi.com/1422-0067/22/6/2823

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https://www.mdpi.com/1422-0067/22/6/2823

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