The Gut Microbiota-Bile Acids-TGR5 Axis Mediates Eucommia ulmoides Leaf Extract Alleviation of Injury to Colonic Epithelium Integrity

The Gut Microbiota-Bile Acids-TGR5 Axis Mediates Eucommia ulmoides Leaf Extract Alleviation of Injury to Colonic Epithelium Integrity

Eucommia ulmoides leaves (EL) are rich in phenolic acids and flavonoids, showing enhancing intestinal health effects. The intestinal microbiota-bile acid axis plays important roles in the occurrence and recovery of inflammatory bowel disease (IBD). However, whether EL extract (ELE) has regulatory ef...

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Bibliographic Details
Main Authors: Zhenya Zhai, Kai-Min Niu, Yichun Liu, Chong Lin, Xin Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Microbiology
Subjects:
Eucommia ulmoides leaves extracts
inflammatory bowel disease
gut microbiota
bile acids
epithelial barrier
Caco-2
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2021.727681/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2021.727681/full

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