Cryptolepine Suppresses Colorectal Cancer Cell Proliferation, Stemness, and Metastatic Processes by Inhibiting WNT/β-Catenin Signaling

Cryptolepine Suppresses Colorectal Cancer Cell Proliferation, Stemness, and Metastatic Processes by Inhibiting WNT/β-Catenin Signaling

Colorectal cancer (CRC) is the third most frequent cancer and the second leading cause of cancer-related deaths globally. Evidence shows that over 90% of CRC cases are initiated by a deregulated Wingless Integrated Type-1 (WNT)/β-catenin signaling pathway. The WNT/β-catenin pathway also promotes CRC...

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Detalles Bibliográficos
Autores principales: Jude Tetteh Quarshie, Kwadwo Fosu, Nicholas Awuku Offei, Augustine Kojo Sobo, Osbourne Quaye, Anastasia Rosebud Aikins
Formato: Artículo
Lenguaje:English
Publicado: MDPI AG 2023-07-01
Colección:Pharmaceuticals
Materias:
cryptolepine
WNT/β-catenin signaling
colorectal cancer
proliferation
stemness
metastasis
Acceso en línea:https://www.mdpi.com/1424-8247/16/7/1026

Internet

https://www.mdpi.com/1424-8247/16/7/1026

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