microRNA-186 in extracellular vesicles from bone marrow mesenchymal stem cells alleviates idiopathic pulmonary fibrosis via interaction with SOX4 and DKK1

microRNA-186 in extracellular vesicles from bone marrow mesenchymal stem cells alleviates idiopathic pulmonary fibrosis via interaction with SOX4 and DKK1

Abstract Background Previous reports have identified that human bone marrow mesenchymal stem cell-derived extracellular vesicles (BMSC-EVs) with their cargo microRNAs (miRNAs) are a promising therapeutic approach for the treatment of idiopathic pulmonary fibrosis (IPF). Therefore, we explored whethe...

Full description

Bibliographic Details
Main Authors: Jing Zhou, Yang Lin, Xiuhua Kang, Zhicheng Liu, Wei Zhang, Fei Xu
Format: Article
Language:English
Published: BMC 2021-02-01
Series:Stem Cell Research & Therapy
Subjects:
Idiopathic pulmonary fibrosis
Fibroblasts
Human bone marrow mesenchymal stem cells
Extracellular vesicles
microRNA-186
SRY-related HMG box transcription factor 4
Online Access:https://doi.org/10.1186/s13287-020-02083-x

Internet

https://doi.org/10.1186/s13287-020-02083-x

Similar Items