Colonization with <i>Escherichia coli</i> ST131-<i>H</i>30R (<i>H</i>30R) Corresponds with Increased Serum Anti-O25 IgG Levels and Decreased TNFα and IL-10 Responsiveness to <i>H</i>30R

Colonization with <i>Escherichia coli</i> ST131-<i>H</i>30R (<i>H</i>30R) Corresponds with Increased Serum Anti-O25 IgG Levels and Decreased TNFα and IL-10 Responsiveness to <i>H</i>30R

An exceptional gut-colonizing ability may underlie the dramatic epidemiological success of the multidrug-resistant <i>H</i>30R subclone of <i>Escherichia coli</i> sequence type 131 (O25b:K+:H4). In order to inform the development of colonization-preventing measures, we studie...

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Bibliographic Details
Main Authors: Brian D. Johnston, Connie Clabots, Tricia Bender, Stephen B. Porter, Germie van den Dobbelsteen, Jan Poolman, Paul Thuras, James R. Johnson
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Pathogens
Subjects:
<i>Escherichia coli</i> ST131-<i>H</i>30
intestinal colonization
IgG
TNFα
IL-10
antigen-stimulated cytokine release
Online Access:https://www.mdpi.com/2076-0817/12/4/603

Internet

https://www.mdpi.com/2076-0817/12/4/603

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