Engineered inhaled nanocatalytic therapy for ischemic cerebrovascular disease by inducing autophagy of abnormal mitochondria

Abstract Mitochondrial dysfunction and subsequent accumulation of reactive oxygen species (ROS) are key contributors to the pathology of ischemic cerebrovascular disease. Therefore, elimination of ROS and damaged mitochondria is crucial for the effective treatment of this disease. For this purpose,...

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Bibliographic Details
Main Authors: Deping Wang, Bowen Li, Shuchao Wang, Yingjian Hao, Hua Wang, Wei Sun, Jimin Cao, Xin Zhou, Bin Zheng
Format: Article
Language:English
Published: Nature Portfolio 2023-08-01
Series:npj Regenerative Medicine
Online Access:https://doi.org/10.1038/s41536-023-00315-1