SIVA-1 enhances acquired chemotherapeutic drug resistance of gastric cancer in vivo by regulating the ARF/MDM2/p53 pathway

SIVA-1 enhances acquired chemotherapeutic drug resistance of gastric cancer in vivo by regulating the ARF/MDM2/p53 pathway

SIVA-1 has been shown to affect apoptotic processes in various different cell lines, and SIVA-1 significantly contributes to the decreased responsiveness of cancer cells to some chemotherapy agents. However, whether SIVA-1 has potential application in gastric cancer remains unknown. Therefore, the o...

Full description

Bibliographic Details
Main Authors: Xiao-Tong Wang, Lei Li, Zhou Zhu, Yu-Liang Huang, Huan-Huan Chen, Zheng-Yi Shi, Qiao-Ming Deng, Kun Wu, Long-Jie Xia, Wei Mai, Jian-Rong Yang, Fan-Biao Kong
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Heliyon
Subjects:
SIVA-1
Drug resistance
Gastric cancer
ARF
MDM2
p53
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024004250

Internet

http://www.sciencedirect.com/science/article/pii/S2405844024004250

Similar Items