SIVA-1 enhances acquired chemotherapeutic drug resistance of gastric cancer in vivo by regulating the ARF/MDM2/p53 pathway
SIVA-1 has been shown to affect apoptotic processes in various different cell lines, and SIVA-1 significantly contributes to the decreased responsiveness of cancer cells to some chemotherapy agents. However, whether SIVA-1 has potential application in gastric cancer remains unknown. Therefore, the o...
Main Authors: | Xiao-Tong Wang, Lei Li, Zhou Zhu, Yu-Liang Huang, Huan-Huan Chen, Zheng-Yi Shi, Qiao-Ming Deng, Kun Wu, Long-Jie Xia, Wei Mai, Jian-Rong Yang, Fan-Biao Kong |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2024-01-01
|
Series: | Heliyon |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844024004250 |
Similar Items
-
Overexpression of CCDC69 activates p14ARF/MDM2/p53 pathway and confers cisplatin sensitivity
by: Long Cui, et al.
Published: (2019-01-01) -
The p53–Mdm2 interaction and the E3 ligase activity of Mdm2/Mdm4 are conserved from lampreys to humans
by: Venkatesh, Byrappa, et al.
Published: (2016) -
Expanding Roles of the E2F-RB-p53 Pathway in Tumor Suppression
by: Yaxuan Zhou, et al.
Published: (2023-12-01) -
Controlling the Mdm2-Mdmx-p53 Circuit
by: David L. Waning, et al.
Published: (2010-05-01) -
Targeting p53–MDM2 interaction by small-molecule inhibitors: learning from MDM2 inhibitors in clinical trials
by: Haohao Zhu, et al.
Published: (2022-07-01)