Acquired Evolution of Mitochondrial Metabolism Regulated by HNF1B in Ovarian Clear Cell Carcinoma

Acquired Evolution of Mitochondrial Metabolism Regulated by HNF1B in Ovarian Clear Cell Carcinoma

Clear cell carcinoma (CCC) of the ovary exhibits a unique morphology and clinically malignant behavior. The eosinophilic cytoplasm includes abundant glycogen. Although the growth is slow, the prognosis is poor owing to resistance to conventional chemotherapies. CCC often arises in endometriotic cyst...

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Bibliographic Details
Main Authors: Ken Yamaguchi, Sachiko Kitamura, Yoko Furutake, Ryusuke Murakami, Koji Yamanoi, Mana Taki, Masayo Ukita, Junzo Hamanishi, Masaki Mandai
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Cancers
Subjects:
ovarian clear cell carcinoma
metabolism
mitochondrion
Warburg effect
glutathione synthesis
Online Access:https://www.mdpi.com/2072-6694/13/10/2413

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https://www.mdpi.com/2072-6694/13/10/2413

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