Pervasive translation in Mycobacterium tuberculosis

Pervasive translation in Mycobacterium tuberculosis

Most bacterial ORFs are identified by automated prediction algorithms. However, these algorithms often fail to identify ORFs lacking canonical features such as a length of >50 codons or the presence of an upstream Shine-Dalgarno sequence. Here, we use ribosome profiling approaches to identify...

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Bibliographic Details
Main Authors: Carol Smith, Jill G Canestrari, Archer J Wang, Matthew M Champion, Keith M Derbyshire, Todd A Gray, Joseph T Wade
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-03-01
Series:eLife
Subjects:
Mycobacterium tuberculosis
pervasive translation
small protein
sORF
leaderless
Online Access:https://elifesciences.org/articles/73980

Internet

https://elifesciences.org/articles/73980

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