Production and characterization of a human antisperm monoclonal antibody against CD52g for topical contraception in women

Production and characterization of a human antisperm monoclonal antibody against CD52g for topical contraception in women

Background: Approximately 40% of human pregnancies are unintended, indicating a need for more acceptable effective contraception methods. New antibody production systems make it possible to manufacture reagent-grade human monoclonal antibodies (mAbs) for clinical use. We used the Nicotiana platform...

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Bibliographic Details
Main Authors: Gabriela Baldeon-Vaca, Jai G. Marathe, Joseph A. Politch, Emilie Mausser, Jeffrey Pudney, James Doud, Ellena Nador, Larry Zeitlin, Michael Pauly, Thomas R. Moench, Miles Brennan, Kevin J. Whaley, Deborah J. Anderson
Format: Article
Language:English
Published: Elsevier 2021-07-01
Series:EBioMedicine
Subjects:
Contraception
Non-hormonal, Monoclonal antibody
Antisperm antibody
Nicotiana
Sperm
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396421002711

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http://www.sciencedirect.com/science/article/pii/S2352396421002711

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