Human Regulatory Dendritic Cells Develop From Monocytes in Response to Signals From Regulatory and Helper T Cells

Human Regulatory Dendritic Cells Develop From Monocytes in Response to Signals From Regulatory and Helper T Cells

Dendritic cells (DCs) are powerful antigen presenting cells, derived from bone marrow progenitors (cDCs) and monocytes (moDCs), that can shape the immune response by priming either proinflammatory or tolerogenic immune effector cells. The cellular mechanisms responsible for the generation of DCs tha...

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Bibliographic Details
Main Authors: Xiangyue Zhang, Pingping Zheng, Tyler R. Prestwood, Hong Zhang, Yaron Carmi, Lorna L. Tolentino, Nancy Wu, Okmi Choi, Daniel A. Winer, Samuel Strober, Eun-Suk Kang, Michael N. Alonso, Edgar G. Engleman
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Immunology
Subjects:
DCs
DCReg
Tregs
Th
monocytes
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.01982/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.01982/full

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