Constitutively active autophagy in macrophages dampens inflammation through metabolic and post-transcriptional regulation of cytokine production

Constitutively active autophagy in macrophages dampens inflammation through metabolic and post-transcriptional regulation of cytokine production

Summary: Autophagy is an essential cellular process that is deeply integrated with innate immune signaling; however, studies that examine the impact of autophagic modulation in the context of inflammatory conditions are lacking. Here, using mice with a constitutively active variant of the autophagy...

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Bibliographic Details
Main Authors: Jinjin Xu, Lingjia Kong, Blayne A. Oliver, Bihua Li, Elizabeth A. Creasey, Gaelen Guzman, Monica Schenone, Kimberly L. Carey, Steven A. Carr, Daniel B. Graham, Jacques Deguine, Ramnik J. Xavier
Format: Article
Language:English
Published: Elsevier 2023-07-01
Series:Cell Reports
Subjects:
CP: Immunology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723007192

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http://www.sciencedirect.com/science/article/pii/S2211124723007192

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