GM-CSF Expression and Macrophage Polarization in Joints of Undifferentiated Arthritis Patients Evolving to Rheumatoid Arthritis or Psoriatic Arthritis

GM-CSF Expression and Macrophage Polarization in Joints of Undifferentiated Arthritis Patients Evolving to Rheumatoid Arthritis or Psoriatic Arthritis

Background and AimsGM-CSF-dependent macrophage polarization has been demonstrated in rheumatoid arthritis (RA). Our aim was to seek diagnostic/prognostic biomarkers for undifferentiated arthritis (UA) by analyzing GM-CSF expression and source, macrophage polarization and density in joints of patient...

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Bibliographic Details
Main Authors: Sara Fuentelsaz-Romero, Andrea Cuervo, Lizbeth Estrada-Capetillo, Raquel Celis, Raquel García-Campos, Julio Ramírez, Sergi Sastre, Rafael Samaniego, Amaya Puig-Kröger, Juan D. Cañete
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Immunology
Subjects:
GM-CSF
macrophages
synovial tissue
undifferentiated arthritis
psoriatic arthritis
rheumatoid arthritis
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.613975/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2020.613975/full

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