Strategies to investigate protein turnover with fluorescent protein reporters in eukaryotic organisms

Strategies to investigate protein turnover with fluorescent protein reporters in eukaryotic organisms

In higher eukaryotes, defects in regulated protein turnover are intimately linked to development of diseases and aging. Systematic investigation of proteostasis and protein degradation pathways is of high importance for understanding basic cellular events as well as developmental processes in higher...

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Bibliographic Details
Main Authors: Jonathan Trauth, Johannes Scheffer, Sophia Hasenjäger, Christof Taxis
Format: Article
Language:English
Published: AIMS Press 2020-05-01
Series:AIMS Biophysics
Subjects:
fluorescent protein
bfp
cfp
gfp
rfp
photoconvertible fp
fluorescent timer
tandem fp timer
proteasome
proteolysis
protein degradation
ubiquitin-proteasome system
ubiquitin
degron
Online Access:https://www.aimspress.com/article/10.3934/biophy.2020008/fulltext.html

Internet

https://www.aimspress.com/article/10.3934/biophy.2020008/fulltext.html

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