Nonsense-mediated decay machinery in Plasmodium falciparum is inefficient and non-essential

Nonsense-mediated decay machinery in Plasmodium falciparum is inefficient and non-essential

ABSTRACT Nonsense-mediated decay (NMD) is a conserved mRNA quality control process that eliminates transcripts bearing a premature termination codon. In addition to its role in removing erroneous transcripts, NMD is involved in post-transcriptional regulation of gene expression via programmed intron...

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Bibliographic Details
Main Authors: Emma McHugh, Michaela S. Bulloch, Steven Batinovic, Cameron J. Patrick, Drishti K. Sarna, Stuart A. Ralph
Format: Article
Language:English
Published: American Society for Microbiology 2023-08-01
Series:mSphere
Subjects:
mRNA degradation
malaria
nonsense-mediated decay
intron retention
RNA-seq
Online Access:https://journals.asm.org/doi/10.1128/msphere.00233-23

Internet

https://journals.asm.org/doi/10.1128/msphere.00233-23

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