Inhibitory effect of AK-7 mediates by apoptosis, increases DNA fragmentation and caspase-3 activity in human glioblastoma multiforme cells
Sirtuins (SIRTs) which are nicotinamide adenine dinucleotide (NAD+) dependent class III histondeacetylases have a controversial role in cancer. In this study, the effect of pharmacological inhibition of AK-7, a SIRT2 inhibitor, was investigated in U87 glioblastoma multiforme cells. The cytotoxic ef...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Bangladesh Pharmacological Society
2022-06-01
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Series: | Bangladesh Journal of Pharmacology |
Subjects: | |
Online Access: | https://www.banglajol.info/index.php/BJP/article/view/59809 |