A Functional Variant Alters the Binding of <i>Bone morphogenetic protein 2</i> to the Transcription Factor NF-κB to Regulate <i>Bone morphogenetic protein 2</i> Gene Expression and Chicken Abdominal Fat Deposition

A Functional Variant Alters the Binding of <i>Bone morphogenetic protein 2</i> to the Transcription Factor NF-κB to Regulate <i>Bone morphogenetic protein 2</i> Gene Expression and Chicken Abdominal Fat Deposition

In this study, we employed a dual-luciferase reporter assay and electrophoretic mobility shift analysis (EMSA) in vitro to explore whether a 12-base pair (bp) insertion/deletion (InDel) variant (namely g.14798187_14798188insTCCCTGCCCCCT) within intron 2 of the chicken <i>BMP2</i> gene, w...

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Bibliographic Details
Main Authors: Meng Yuan, Xin Liu, Mengdie Wang, Ziwei Li, Hui Li, Li Leng, Shouzhi Wang
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Animals
Subjects:
<i>Bone morphogenetic protein 2</i> (<i>BMP2</i>)
chicken
functional variation
transcriptional regulation
Online Access:https://www.mdpi.com/2076-2615/13/21/3401

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https://www.mdpi.com/2076-2615/13/21/3401

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