Dysregulated Methylation Patterns in Exon IV of the Brain-Derived Neurotrophic Factor (BDNF) Gene in Nicotine Dependence and Changes in BDNF Plasma Levels During Smoking Cessation

Dysregulated Methylation Patterns in Exon IV of the Brain-Derived Neurotrophic Factor (BDNF) Gene in Nicotine Dependence and Changes in BDNF Plasma Levels During Smoking Cessation

IntroductionSeveral studies reported dysregulated protein levels of brain-derived neurotrophic factor (BDNF) in smokers and during cessation. However, the epigenetic regulation of the BDNF gene has not yet been investigated. We measured the plasma levels of BDNF and the epigenetic regulation of exon...

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Bibliographic Details
Main Authors: Kerim Abdelkhalek, Mathias Rhein, Maximilian Deest, Vanessa Buchholz, Stefan Bleich, Ralf Lichtinghagen, Benjamin Vyssoki, Helge Frieling, Marc Muschler, Phileas Johannes Proskynitopoulos, Alexander Glahn
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Psychiatry
Subjects:
tobacco dependence
addiction - smoking
addiction
epigenetic
addict behavior
Online Access:https://www.frontiersin.org/articles/10.3389/fpsyt.2022.897801/full

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https://www.frontiersin.org/articles/10.3389/fpsyt.2022.897801/full

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